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KMID : 0387719950060020185
Korean Journal of Blood Transfusion
1995 Volume.6 No. 2 p.185 ~ p.188
A Case Report of Anti-Jr in pregnant Woman
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Abstract
The high incidence antigen Jra was first identified in 1970 by Stroup and MacIlroy. Anti-Jra was immune antibodies developed by transfusion or pregnancy and occasionally cause hemolytic disease of the newborn and transfusion reaction, but these
usually
mild.
We are reporting the first case of anti-Jra in Korea, which was identified in pregnant woman with transfusion history. The 35 year old preanant woman (G6P4L1D3A1) admitted to treat for incompetent internal os of cervix on department of Obstetrics
and
Gynecology. Prenatal irregular antibody screening was negative. One unit of RBC was transfused at 21 gestational weeks for correction of anemia. One week later, irregular antibody was detected in her serum. The antibody reacted best by indirect
antiglobulin test and panagglutinated all identified cells. The titer was 1:8. The antibody was identified as anti-jra by Dr, Osaka Red Cross Center. Her phenotype of Jra was Jr(a-), but there was no Jr(a-) person in her family.
She might have anti-Jra in her serum with undetectable level due to multiple pregnancies. In this case, the development of anti-Jra was stimulated by one unit of RBC transfusion with anamnestic reaction. The titer of anti-Jra was gradually
reduced
during pregnant period. She delivered at 37 gestational weeks by cesarian section. The baby was clinically well at birth and typed as Jr(a+).
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